I was introduced to the office manager informally by a friend, and set up an informational interview with her, without knowing any specific openings. After talking to me about half an hour about my general backgrounds and skills, she seemed to like me, and then said, one of our teams was looking for someone to fill an administrative position. It is probably not what you are looking for, since you have a master's degree. But are you willing to try? I said, yes!! I am willing to take any job, to get my foot in the door.