You process over 10x as much email as you otherwise would with another company. I view this as a pretty fun challenge but I know it can bury some people. It isn't unheard of to have ~5-10K+ unread emails in a box...all somehow seeming urgent.
With 50K+ employees, it can be tough to navigate the structure when seeking an answer. People rotate through teams often and this means you have to be very resourceful and sharp to solve challenges in cross-product-team scenarios.
Thought it's fun and exciting to work here, you may find yourself looking at the clock to notice that you've been at work for 12 hours. I suppose this says something good about the desire to be there without counting the hours away, but takes its toll on your social & personal life schedule if you're not careful to balance it well.